Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis

Lin-Yi Li; Jie Zhou; Cun-Hao Mao; Diwas Sunchuri; Zhuo-Da Yang; Xu-Dong Tian; Zi-Nan Zhan; Zhu-Ling Guo

doi:doi:10.11648/j.sjph.20241203.13

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Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis

Lin-Yi Li, Jie Zhou, Cun-Hao Mao, Diwas Sunchuri, Zhuo-Da Yang, Xu-Dong Tian, Zi-Nan Zhan, Zhu-Ling Guo^*

Published in Science Journal of Public Health (Volume 12, Issue 3)

Received: 22 April 2024 Accepted: 9 May 2024 Published: 24 May 2024

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Abstract

Agarwood, as a precious medicinal material with distinctive characteristics from Hainan, has been shown in recent studies to possess significant anti-inflammatory and antibacterial properties. With the rapid growth in public recognition of health concepts, oral health has garnered increased attention. The main focus of this study is the impact of agarwood extracts on the oral-gut axis microbiota. The relationship between the oral and gut microbiota is closely intertwined, where oral microbiota can directly colonize the intestine via saliva and other means, altering the original microbial composition of the gut and leading to dysbiosis. For instance, Porphyromonas gingivalis significantly increases in patients with gingivitis and periodontitis, as it can tolerate the acidic environment of the stomach and colonize the intestines through the gastric barrier. Therefore, oral health can affect intestinal health. Additionally, oral lesions are evident in patients with intestinal inflammation; such patients, like those with IBD, exhibit a significant accumulation of oral bacteria in the intestines. Although IBD primarily affects the intestines, its extraintestinal symptoms, often prominently displayed, include oral manifestations. Hence, intestinal health can also influence oral health. Agarwood extracts inhibit pathogenic oral microbiota, impedes their colonization in the intestine, and consequently reduces the likelihood of inflammatory bowel disease.. This article, by introducing the microbiota of periodontitis and the pathogenesis of inflammatory bowel disease, along with extraintestinal symptoms, the preventive and inhibitory mechanisms of agarwood extract on the associated microbiota are analyzed, providing new insights for the treatment of such patients. It underscores the importance of maintaining oral hygiene and preventing oral diseases as well.

Published in	Science Journal of Public Health (Volume 12, Issue 3)
DOI	10.11648/j.sjph.20241203.13
Page(s)	79-82
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Agarwood, Oral-Gut Axis Microbiota, Inflammation, Periodontitis, Inflammatory Bowel Disease

References

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APA Style

Li, L., Zhou, J., Mao, C., Sunchuri, D., Yang, Z., et al. (2024). Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Science Journal of Public Health, 12(3), 79-82. https://doi.org/10.11648/j.sjph.20241203.13

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ACS Style

Li, L.; Zhou, J.; Mao, C.; Sunchuri, D.; Yang, Z., et al. Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Sci. J. Public Health 2024, 12(3), 79-82. doi: 10.11648/j.sjph.20241203.13

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AMA Style

Li L, Zhou J, Mao C, Sunchuri D, Yang Z, et al. Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Sci J Public Health. 2024;12(3):79-82. doi: 10.11648/j.sjph.20241203.13

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@article{10.11648/j.sjph.20241203.13,
  author = {Lin-Yi Li and Jie Zhou and Cun-Hao Mao and Diwas Sunchuri and Zhuo-Da Yang and Xu-Dong Tian and Zi-Nan Zhan and Zhu-Ling Guo},
  title = {Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis
},
  journal = {Science Journal of Public Health},
  volume = {12},
  number = {3},
  pages = {79-82},
  doi = {10.11648/j.sjph.20241203.13},
  url = {https://doi.org/10.11648/j.sjph.20241203.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20241203.13},
  abstract = {Agarwood, as a precious medicinal material with distinctive characteristics from Hainan, has been shown in recent studies to possess significant anti-inflammatory and antibacterial properties. With the rapid growth in public recognition of health concepts, oral health has garnered increased attention. The main focus of this study is the impact of agarwood extracts on the oral-gut axis microbiota. The relationship between the oral and gut microbiota is closely intertwined, where oral microbiota can directly colonize the intestine via saliva and other means, altering the original microbial composition of the gut and leading to dysbiosis. For instance, Porphyromonas gingivalis significantly increases in patients with gingivitis and periodontitis, as it can tolerate the acidic environment of the stomach and colonize the intestines through the gastric barrier. Therefore, oral health can affect intestinal health. Additionally, oral lesions are evident in patients with intestinal inflammation; such patients, like those with IBD, exhibit a significant accumulation of oral bacteria in the intestines. Although IBD primarily affects the intestines, its extraintestinal symptoms, often prominently displayed, include oral manifestations. Hence, intestinal health can also influence oral health. Agarwood extracts inhibit pathogenic oral microbiota, impedes their colonization in the intestine, and consequently reduces the likelihood of inflammatory bowel disease.. This article, by introducing the microbiota of periodontitis and the pathogenesis of inflammatory bowel disease, along with extraintestinal symptoms, the preventive and inhibitory mechanisms of agarwood extract on the associated microbiota are analyzed, providing new insights for the treatment of such patients. It underscores the importance of maintaining oral hygiene and preventing oral diseases as well.
},
 year = {2024}
}

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TY  - JOUR
T1  - Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis

AU  - Lin-Yi Li
AU  - Jie Zhou
AU  - Cun-Hao Mao
AU  - Diwas Sunchuri
AU  - Zhuo-Da Yang
AU  - Xu-Dong Tian
AU  - Zi-Nan Zhan
AU  - Zhu-Ling Guo
Y1  - 2024/05/24
PY  - 2024
N1  - https://doi.org/10.11648/j.sjph.20241203.13
DO  - 10.11648/j.sjph.20241203.13
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 79
EP  - 82
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20241203.13
AB  - Agarwood, as a precious medicinal material with distinctive characteristics from Hainan, has been shown in recent studies to possess significant anti-inflammatory and antibacterial properties. With the rapid growth in public recognition of health concepts, oral health has garnered increased attention. The main focus of this study is the impact of agarwood extracts on the oral-gut axis microbiota. The relationship between the oral and gut microbiota is closely intertwined, where oral microbiota can directly colonize the intestine via saliva and other means, altering the original microbial composition of the gut and leading to dysbiosis. For instance, Porphyromonas gingivalis significantly increases in patients with gingivitis and periodontitis, as it can tolerate the acidic environment of the stomach and colonize the intestines through the gastric barrier. Therefore, oral health can affect intestinal health. Additionally, oral lesions are evident in patients with intestinal inflammation; such patients, like those with IBD, exhibit a significant accumulation of oral bacteria in the intestines. Although IBD primarily affects the intestines, its extraintestinal symptoms, often prominently displayed, include oral manifestations. Hence, intestinal health can also influence oral health. Agarwood extracts inhibit pathogenic oral microbiota, impedes their colonization in the intestine, and consequently reduces the likelihood of inflammatory bowel disease.. This article, by introducing the microbiota of periodontitis and the pathogenesis of inflammatory bowel disease, along with extraintestinal symptoms, the preventive and inhibitory mechanisms of agarwood extract on the associated microbiota are analyzed, providing new insights for the treatment of such patients. It underscores the importance of maintaining oral hygiene and preventing oral diseases as well.

VL  - 12
IS  - 3
ER  -

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Author Information

Lin-Yi Li

School of Dentistry, Hainan Medical University, Haikou, PR China
Jie Zhou

School of Dentistry, Hainan Medical University, Haikou, PR China
Cun-Hao Mao

School of Dentistry, Hainan Medical University, Haikou, PR China
Diwas Sunchuri

School of International Education, Hainan Medical University, Haikou, PR China
Zhuo-Da Yang

School of Dentistry, Hainan Medical University, Haikou, PR China
Xu-Dong Tian

School of Dentistry, Hainan Medical University, Haikou, PR China
Zi-Nan Zhan

School of Dentistry, Hainan Medical University, Haikou, PR China
Zhu-Ling Guo

School of Dentistry, Hainan Medical University, Haikou, PR China; Department of Health Management Center, The First Affiliated Hospital of Hainan Medical University, Haikou, PR China

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APA Style

Li, L., Zhou, J., Mao, C., Sunchuri, D., Yang, Z., et al. (2024). Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Science Journal of Public Health, 12(3), 79-82. https://doi.org/10.11648/j.sjph.20241203.13

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ACS Style

Li, L.; Zhou, J.; Mao, C.; Sunchuri, D.; Yang, Z., et al. Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Sci. J. Public Health 2024, 12(3), 79-82. doi: 10.11648/j.sjph.20241203.13

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AMA Style

Li L, Zhou J, Mao C, Sunchuri D, Yang Z, et al. Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis. Sci J Public Health. 2024;12(3):79-82. doi: 10.11648/j.sjph.20241203.13

Copy | Download

@article{10.11648/j.sjph.20241203.13,
  author = {Lin-Yi Li and Jie Zhou and Cun-Hao Mao and Diwas Sunchuri and Zhuo-Da Yang and Xu-Dong Tian and Zi-Nan Zhan and Zhu-Ling Guo},
  title = {Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis
},
  journal = {Science Journal of Public Health},
  volume = {12},
  number = {3},
  pages = {79-82},
  doi = {10.11648/j.sjph.20241203.13},
  url = {https://doi.org/10.11648/j.sjph.20241203.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20241203.13},
  abstract = {Agarwood, as a precious medicinal material with distinctive characteristics from Hainan, has been shown in recent studies to possess significant anti-inflammatory and antibacterial properties. With the rapid growth in public recognition of health concepts, oral health has garnered increased attention. The main focus of this study is the impact of agarwood extracts on the oral-gut axis microbiota. The relationship between the oral and gut microbiota is closely intertwined, where oral microbiota can directly colonize the intestine via saliva and other means, altering the original microbial composition of the gut and leading to dysbiosis. For instance, Porphyromonas gingivalis significantly increases in patients with gingivitis and periodontitis, as it can tolerate the acidic environment of the stomach and colonize the intestines through the gastric barrier. Therefore, oral health can affect intestinal health. Additionally, oral lesions are evident in patients with intestinal inflammation; such patients, like those with IBD, exhibit a significant accumulation of oral bacteria in the intestines. Although IBD primarily affects the intestines, its extraintestinal symptoms, often prominently displayed, include oral manifestations. Hence, intestinal health can also influence oral health. Agarwood extracts inhibit pathogenic oral microbiota, impedes their colonization in the intestine, and consequently reduces the likelihood of inflammatory bowel disease.. This article, by introducing the microbiota of periodontitis and the pathogenesis of inflammatory bowel disease, along with extraintestinal symptoms, the preventive and inhibitory mechanisms of agarwood extract on the associated microbiota are analyzed, providing new insights for the treatment of such patients. It underscores the importance of maintaining oral hygiene and preventing oral diseases as well.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Exploration of the Effects of Agarwood Extract on the Inflammtory Microbiota in the Oral-Gut Axis

AU  - Lin-Yi Li
AU  - Jie Zhou
AU  - Cun-Hao Mao
AU  - Diwas Sunchuri
AU  - Zhuo-Da Yang
AU  - Xu-Dong Tian
AU  - Zi-Nan Zhan
AU  - Zhu-Ling Guo
Y1  - 2024/05/24
PY  - 2024
N1  - https://doi.org/10.11648/j.sjph.20241203.13
DO  - 10.11648/j.sjph.20241203.13
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 79
EP  - 82
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20241203.13
AB  - Agarwood, as a precious medicinal material with distinctive characteristics from Hainan, has been shown in recent studies to possess significant anti-inflammatory and antibacterial properties. With the rapid growth in public recognition of health concepts, oral health has garnered increased attention. The main focus of this study is the impact of agarwood extracts on the oral-gut axis microbiota. The relationship between the oral and gut microbiota is closely intertwined, where oral microbiota can directly colonize the intestine via saliva and other means, altering the original microbial composition of the gut and leading to dysbiosis. For instance, Porphyromonas gingivalis significantly increases in patients with gingivitis and periodontitis, as it can tolerate the acidic environment of the stomach and colonize the intestines through the gastric barrier. Therefore, oral health can affect intestinal health. Additionally, oral lesions are evident in patients with intestinal inflammation; such patients, like those with IBD, exhibit a significant accumulation of oral bacteria in the intestines. Although IBD primarily affects the intestines, its extraintestinal symptoms, often prominently displayed, include oral manifestations. Hence, intestinal health can also influence oral health. Agarwood extracts inhibit pathogenic oral microbiota, impedes their colonization in the intestine, and consequently reduces the likelihood of inflammatory bowel disease.. This article, by introducing the microbiota of periodontitis and the pathogenesis of inflammatory bowel disease, along with extraintestinal symptoms, the preventive and inhibitory mechanisms of agarwood extract on the associated microbiota are analyzed, providing new insights for the treatment of such patients. It underscores the importance of maintaining oral hygiene and preventing oral diseases as well.

VL  - 12
IS  - 3
ER  -

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